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    Chapter

    siRNA Loaded in Drug Delivery Nanosystems as a Strategy for Breast Cancer Treatment

    Advances in genetic sequencing techniques have enabled the knowledge of promising molecules, including siRNA (short interfering RNA), a mechanism of gene silencing directed against the mRNA strand that prevent...

    Kammila Martins Nicolau Costa, Luana Beatriz Camêlo de Sousa, Demis Ferreira de Melo (2022)

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    Chapter

    Bleeding in the Setting of Lymphoma, with a Focus on Waldenström Macroglobulinaemia

    Bleeding symptoms are common in haematological malignancies, with 26% experiencing minor to moderate bleeding and 6% experiencing major or fatal haemorrhages. However, bleeding is underreported and remains poo...

    Simone A. Brysland, Muhammad Gohar Maqbool, Dipti Talaulikar, Elizabeth E. Gardiner (2022)

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    Chapter

    The Role of PARP Inhibitors in the Treatment of Advanced Epithelial Ovarian Carcinoma

    Epithelial high-grade serous and endometrioid ovarian carcinoma (HGOC) is the most common subtype of epithelial ovarian cancer (EOC) and is diagnosed in most patients at an advanced stage and is characterized ...

    Seda Kahraman, Mehmet Ali Nahit Şendur (2022)

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    Chapter

    Earthquakes and Tsunamis: Natural Hazards Over the Aegean Archipelago

    The Aegean Sea is characterized by a strong human presence and significant achievements in all sectors of human activity for thousands of years. Its geological and geomorphological setting has been shaped by i...

    Marilia Gogou, Spyridon Mavroulis, Niki Evelpidou, Efthymis Lekkas (2022)

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    Chapter

    Circulating Tumor Cells in Head and Neck Cancer

    Circulating tumor cells (CTCs) are a rare subpopulation of cells with potential use in a range of clinical applications for better management of patients with cancers. For example, they have been recognized as...

    Tasfik Ul Haque Pronoy, Sharmin Aktar, Kazi Soha, Md. Arifur Rahman, Md. Nurujjaman (2022)

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    Chapter

    The Effect of Harvest on Forest Soil N2O Fluxes: A Review

    Forest harvests that include clear-cutting, selective cutting, and thinning are widely used management practices. On a global scale, about 30% of forests are harvested to produce timber and non-timber forest p...

    Hui Zhang, Yixiang Wang (2022)

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    Chapter

    Assessment and Contribution of Biomass Residues to Renewable Energy Resources in Egypt

    Although using fossil fuels in energy sector has led to economic growth in different fields, it caused an increase in greenhouse gas emissions, in consequence, global warming and climate change. Biomass use is...

    Mahmoud M. Abdel daiem, Noha Said (2022)

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    Chapter

    Intraocular Lymphoma

    Intraocular lymphomas are rare, non-Hodgkin, large B-cell lymphomas affecting the vitreous, the retina, the retinal pigment epithelium (RPE) or the uvea tract. Vitreoretinal lymphomas (VRLs) are the most commo...

    Konstantina Riri, Dimitrios Kalogeropoulos, Andreas Mitsios, Ioanna Ploumi (2022)

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    Chapter

    Evaluation of the Wind Energy Potential in Morocco

    Lately, renewable energy sources have been an issue of renewed interest in developing countries, and Morocco imported about 90% of its energy needs. For this reason, the government has made a commitment to imp...

    Mohammed Boussetta, Abdelilah Et-Taleby (2022)

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    Chapter

    The Effects of Angiotensin-Converting Enzyme Inhibitors on Metastasis-Associated Myeloid Cells

    Myeloid-derived suppressor cells (MDSCs) enable metastasis by inhibiting innate and adaptive immune responses. During pre-metastatic niche formation, MDSCs lack their T-cell immunosuppressive function; instead...

    Dora L. Vallejo-Ardila, Rafael Parra-Medina, Alba Combita, Andrés F. Cardona (2022)

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    Chapter

    Forest Soils and Greenhouse Gas Emissions in the Natural Forest, Degraded, and Plantation Ecosystems

    The primary greenhouse gases (GHGs) in the natural forest ecosystems are carbon (C) and nitrogen (N) cycles. Carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) are the principal gases that cycle between...

    Yahya Kooch, Mehdi Heydari, Manuel Esteban Lucas-Borja, Isabel Miralles (2022)

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    Chapter

    Forest Management Systems and Carbon, Nitrogen, Phosphorous Cycling

    The global cycling of carbon (C), nitrogen (N), and phosphorus (P) are recognised as extremely important processes provided by the biosphere. The biogeochemical cycles of these elements are essential to mainta...

    Yahya Kooch, Mehdi Heydari, Manuel Esteban Lucas-Borja, Isabel Miralles (2022)

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    Chapter

    Managed Forests and Methane: Recent Research and Prospects for Best Management Practices

    Methane (CH4) accounts for 25–30% of anthropogenic climate forcing and is an attractive focus for climate mitigation due to its short half-life in the atmosphere, and the fact that CH4 emissions are unintended an...

    Sean C. Thomas, Adam S. Gorgolewski, Juliana Vantellingen (2022)

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    Chapter

    Molecular Signatures in Acute Myeloid Leukemia: From Diagnosis to Targeted Therapy and Drug Repositioning

    Acute myeloid leukemia (AML) is a heterogeneous disease defined by the proliferation of immature myeloid progenitor cells in the bone marrow that impairs normal blood cell development and leads to bone marrow ...

    Nurdan Kelesoglu, Betul Karademir-Yilmaz, Kazim Yalcin Arga (2022)

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    Chapter

    The Role of EBV and Immune Deregulation in the Development of IgG4-Related Diseases

    IgG4-related disease (IgG4-RD) is a recently recognized multi-organ fibro-inflammatory condition characterized by a tendency to form mass lesions in multiple sites, a dense lymphoplasmacytic infiltrate dominat...

    Alessandro Ginori, Luigi Spagnoli, Maria R. Ambrosio (2022)

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    Chapter

    Nutrient Transporters: New Molecular Targets for Triple Negative Breast Cancer in Type 2 Diabetics

    Breast cancer is the most common malignancy among women worldwide and is also the leading cause of cancer-related death in this gender. Type 2 diabetes mellitus (T2D) is one of the most common chronic diseases...

    Cláudia Silva, Fátima Martel (2022)

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    Chapter

    Typical Mathematical and Statistical Methods in the Cycle of Carbon and Nitrogen in Forest Soil

    The coupled carbon-nitrogen cycle in the terrestrial ecosystem is a complex system between plant and soil, directly impacting the biosphere. The typical mathematical and statistical methods in studying the cyc...

    Jinying Tan, Wenjie Jin, Zhibin Sun (2022)

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    Chapter

    Molecular Subtypes of High-Grade Serous Ovarian Carcinoma

    High-grade serous carcinoma (HGSC) is the most widespread and aggressive histotype of ovarian cancer. In recent decades, significant efforts have been made to improve HGSC survival rate and develop personalize...

    Aleksandra Asaturova, Anna Tregubova, Alina Magnaeva (2022)

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    Chapter

    Contribution of Renewable Energy in Algeria

    Algeria, being amongst the biggest natural gas-producing countries in the world and belonging to top three oil producers in Africa, is supporting the development of its renewable energy resources. These clean ...

    Y. Himri, S. Rehman, A. Mostafaeipour, S. Himri, M. Merzouk, N. Kasbadji Merzouk (2022)

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    Chapter

    The Impact of Climate Change on Forest Hydrology

    Forests, whose regulating action on water resources is essential, are the biome that may particularly suffer from the effects of climate change. An analysis of the effects of global warming on forest hydrology...

    Demetrio Antonio Zema, Manuel Esteban Lucas-Borja (2022)

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