2,836,722 Result(s)
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Chapter
siRNA Loaded in Drug Delivery Nanosystems as a Strategy for Breast Cancer Treatment
Advances in genetic sequencing techniques have enabled the knowledge of promising molecules, including siRNA (short interfering RNA), a mechanism of gene silencing directed against the mRNA strand that prevent...
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Chapter
Bleeding in the Setting of Lymphoma, with a Focus on Waldenström Macroglobulinaemia
Bleeding symptoms are common in haematological malignancies, with 26% experiencing minor to moderate bleeding and 6% experiencing major or fatal haemorrhages. However, bleeding is underreported and remains poo...
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Chapter
The Role of PARP Inhibitors in the Treatment of Advanced Epithelial Ovarian Carcinoma
Epithelial high-grade serous and endometrioid ovarian carcinoma (HGOC) is the most common subtype of epithelial ovarian cancer (EOC) and is diagnosed in most patients at an advanced stage and is characterized ...
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Chapter
Earthquakes and Tsunamis: Natural Hazards Over the Aegean Archipelago
The Aegean Sea is characterized by a strong human presence and significant achievements in all sectors of human activity for thousands of years. Its geological and geomorphological setting has been shaped by i...
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Chapter
Circulating Tumor Cells in Head and Neck Cancer
Circulating tumor cells (CTCs) are a rare subpopulation of cells with potential use in a range of clinical applications for better management of patients with cancers. For example, they have been recognized as...
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Chapter
The Effect of Harvest on Forest Soil N2O Fluxes: A Review
Forest harvests that include clear-cutting, selective cutting, and thinning are widely used management practices. On a global scale, about 30% of forests are harvested to produce timber and non-timber forest p...
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Chapter
Assessment and Contribution of Biomass Residues to Renewable Energy Resources in Egypt
Although using fossil fuels in energy sector has led to economic growth in different fields, it caused an increase in greenhouse gas emissions, in consequence, global warming and climate change. Biomass use is...
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Chapter
Intraocular Lymphoma
Intraocular lymphomas are rare, non-Hodgkin, large B-cell lymphomas affecting the vitreous, the retina, the retinal pigment epithelium (RPE) or the uvea tract. Vitreoretinal lymphomas (VRLs) are the most commo...
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Chapter
Evaluation of the Wind Energy Potential in Morocco
Lately, renewable energy sources have been an issue of renewed interest in developing countries, and Morocco imported about 90% of its energy needs. For this reason, the government has made a commitment to imp...
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Chapter
The Effects of Angiotensin-Converting Enzyme Inhibitors on Metastasis-Associated Myeloid Cells
Myeloid-derived suppressor cells (MDSCs) enable metastasis by inhibiting innate and adaptive immune responses. During pre-metastatic niche formation, MDSCs lack their T-cell immunosuppressive function; instead...
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Chapter
Forest Soils and Greenhouse Gas Emissions in the Natural Forest, Degraded, and Plantation Ecosystems
The primary greenhouse gases (GHGs) in the natural forest ecosystems are carbon (C) and nitrogen (N) cycles. Carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) are the principal gases that cycle between...
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Chapter
Forest Management Systems and Carbon, Nitrogen, Phosphorous Cycling
The global cycling of carbon (C), nitrogen (N), and phosphorus (P) are recognised as extremely important processes provided by the biosphere. The biogeochemical cycles of these elements are essential to mainta...
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Chapter
Managed Forests and Methane: Recent Research and Prospects for Best Management Practices
Methane (CH4) accounts for 25–30% of anthropogenic climate forcing and is an attractive focus for climate mitigation due to its short half-life in the atmosphere, and the fact that CH4 emissions are unintended an...
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Chapter
Molecular Signatures in Acute Myeloid Leukemia: From Diagnosis to Targeted Therapy and Drug Repositioning
Acute myeloid leukemia (AML) is a heterogeneous disease defined by the proliferation of immature myeloid progenitor cells in the bone marrow that impairs normal blood cell development and leads to bone marrow ...
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Chapter
The Role of EBV and Immune Deregulation in the Development of IgG4-Related Diseases
IgG4-related disease (IgG4-RD) is a recently recognized multi-organ fibro-inflammatory condition characterized by a tendency to form mass lesions in multiple sites, a dense lymphoplasmacytic infiltrate dominat...
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Chapter
Nutrient Transporters: New Molecular Targets for Triple Negative Breast Cancer in Type 2 Diabetics
Breast cancer is the most common malignancy among women worldwide and is also the leading cause of cancer-related death in this gender. Type 2 diabetes mellitus (T2D) is one of the most common chronic diseases...
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Chapter
Typical Mathematical and Statistical Methods in the Cycle of Carbon and Nitrogen in Forest Soil
The coupled carbon-nitrogen cycle in the terrestrial ecosystem is a complex system between plant and soil, directly impacting the biosphere. The typical mathematical and statistical methods in studying the cyc...
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Chapter
Molecular Subtypes of High-Grade Serous Ovarian Carcinoma
High-grade serous carcinoma (HGSC) is the most widespread and aggressive histotype of ovarian cancer. In recent decades, significant efforts have been made to improve HGSC survival rate and develop personalize...
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Chapter
Contribution of Renewable Energy in Algeria
Algeria, being amongst the biggest natural gas-producing countries in the world and belonging to top three oil producers in Africa, is supporting the development of its renewable energy resources. These clean ...
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Chapter
The Impact of Climate Change on Forest Hydrology
Forests, whose regulating action on water resources is essential, are the biome that may particularly suffer from the effects of climate change. An analysis of the effects of global warming on forest hydrology...